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Ballenger was first published in 1908. It has appeared in 10 languages and sold 150,000 copies worldwide. Over two-thirds of the authors are new to this edition. The editorial leadership for the 17th edition has been expanded to include P. Ashley Wackym as Editor, and it includes 101 chapters (increased from 67) with sections on otology and neurotology, rhinology, facial plastic and reconstructive surgery, pediatric otorhinolaryngology, laryngology and bronchoesophagology, head and neck surgery and increased emphasis on molecular medicine. Color illustrations appear throughout this edition. The presentation of basic science underlying clinical otorhinolaryngology has been expanded and chapters on clinical topics are structured to provide comprehensive coverage for the clinicians. Disorders of smell and taste, balance and hearing, voice, speech and language are also emphasized provide comprehensive coverage of the discipline. The 17th edition presents a comprehensive compendium of current knowledge in otorhinolaryngology head and neck surgery and provides full coverage needed by practitioners in the 21st century. New chapters include Stereotactic radiosurgery, Biofilms, Outcomes and clinical research, Robotic surgery and Chemoradiation. Senior authors were chosen not only for original contributions but also for their intellectual leadership of the specialty. Basic science and clinical chapters stress the role of molecular biology in the pathogenesis of disease. Throughout, the genetic basis of disease has been emphasized. The book is a unique blend of state-of-the-art clinical techniques, methods and outcomes together with coverage of basic mechanisms and science. It provides students, residents, fellows and practitioners with the understanding necessary to participate fully in the use of molecular biology in therapy.