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Viruses: Biology, Application, and Control is a concise textbook for advanced undergraduate and graduate students covering the essential aspects of virology included in biomedical science courses. It is an updated and expanded version of David Harpers Molecular Virology, Second Edition. Focusing on key mechanisms and developments, Viruses presents many new sections that cover recent advances including virus evolution, emerging infections, virus extinction, control of infections, antiviral drugs, gene therapy, bacteriophage therapy, and diagnostics. The first chapters introduce the reader to the structure and nature of viruses, including their classification and evolution. As viruses cause widespread and serious disease, the ensuing chapters explain how they interact with the immune system and the different ways we try to defeat them: vaccines, antiviral drugs, and immunotherapy. There is also coverage of laboratory methods for viral detection and laboratory diagnosis. While viruses do cause disease, many do not, and their special biology means they can have beneficial uses. This aspect of viruses is not neglected. Finally, one of the most interesting areas in virology, and one given extensive coverage here, is how new viruses emerge and establish themselves. Viruses: Biology, Application, and Control is a rigorous treatment of the molecular side of virology and its conceptual approach makes it an essential text for students and non-specialists.
For many years the use of chemical agents such as pesticides and herbicides has been effective in controlling the many varieties of pests that infest both agricultural crops and backyard gardens. However, these pests are gradually becoming resistant to these agents, because the agents themselves are acting as selective factors making the pests better and better able to resist and persist. As a result, the use of biological controlling agents is increasing. This book is a comprehensive and authoritative handbook of biological control. Key Features * Introduction (preface plus 2 chapters) * Principles and processes (12 chapters) * Agents, biology, and methods (6 chapters) * Applications (10 chapters) * Research (2 chapters)
Mass Production of Beneficial Organisms: Invertebrates and Entomopathogens is an essential reference and teaching tool for researchers in developed and developing countries working to produce "natural enemies" in biological control and integrated pest management programs. As we become aware of the negative impact of pesticides in human health and on the environment, interest is rapidly increasing in developing biological pest control alternatives. Tremendous advances have been made in beneficial organism technology, such as insect predators and parasitoids, mite predators, entomopathogenic nematodes, fungi, bacteria, and viruses. However, developing techniques to mass produce these biological control agents is not enough if the cost of commercialization is prohibitive. Advancing mass production to the level of economic feasibility is critical, so these new technologies can compete in the open market. This book educates academic and industry researchers, and enables further development of mass production so new technologies can compete in the open market. It is also an excellent resource for those researching beneficial arthropod mass production and technologies for other uses, including for study and application in biotechnology and biomedical research. Focuses on techniques for mass production of beneficial organisms and methods of evaluation and quality assessment Organizes and presents the most advanced and current knowledge on methods to mass produce beneficial organisms in response to the increased global demand for alternatives to chemical pesticides for biological control producers Includes a team of highly respected editors and authors with broad expertise in these areas
Reverse genetics, the genetic manipulation of RNA viruses to create a wild-type or modified virus, has led to important advances in our understanding of viral gene function and interaction with host cells. Since many severe viral human and animal pathogens are RNA viruses, including those responsible for polio, measles, rotaviral diarrhoea and influenza infections, it is also an extremely powerful technique with important potential application for the prevention and control of a range of human and animal viral diseases. Reverse Genetics of RNA Viruses provides a comprehensive account of the very latest developments in reverse genetics of RNA viruses through a wide range of applications within each of the core virus groups including; positive sense, negative sense and double stranded RNA viruses. Written by a team of international experts in the field, it provides a unique insight into how the field has developed, what problems are being addressed now and where applications may lead in the future. It will prove invaluable to bioscience, medical and veterinary students, those starting research in this area as well as other researchers and teachers needing to update their knowledge of this fast-moving field. An authoritative, comprehensive overview of reverse genetics in RNA Viruses. Includes numerous examples of cutting- edge applications of reverse genetics within each of the RNA viral groups. Written by a team of international experts, including some of the leading researchers in the field.
Completely revised and updated to reflect important advances in the field, Principles of Virology, Second Edition continues to fill the gap between simple introductory texts and very advanced reviews of major virus families, introducing upper–level undergraduates, graduate students, and medical students to all aspects of virology. The second edition retains all of the defining and much–praised features of the first edition, focusing on concepts and principles and presenting a comprehensive treatment from molecular biology to pathogenesis and infection control. Written in an engagingly readable style and generously illustrated with over 400 full–color illustrations, this approachable volume offers detailed examples that illustrate common principles, specific strategies adopted by different viruses to ensure their reproduction, and the current state of virology research. The book is divided into chapters that focus on specific topics rather than individual viruses, and allows the student to visualize common themes that cut across virus families, emphasizing the shared features of different viruses. Drawing on the extensive teaching experience of each of its distinguished authors, Principles of Virology illustrates why and how animal viruses are studied and demonstrates, using well–studied systems, how the knowledge gained from such model viruses can be used to study viral systems about which our knowledge is still quite limited. A thorough introduction to principles of viral pathogenesis, a broad view of viral evolution, a discussion of how viruses were discovered, and how the discipline of virology came to be are also provided. A variety of special boxes highlight key experiments, background material, caveats, and much more. The text focuses on concepts and principles and covers not only aspects of molecular biology, but also pathogenesis, evolution, emergence, and control, and will also be a valuable resource for practicing physicians and scientists. New in the Second Edition Completely revised pathogenesis chapters Pathogenicity Snapshots: an appendix highlighting teaching points for major viral diseases Expanded appendix on viral life cycles New chapter on viral genomes and coding strategies Detailed glossary Expanded references after each chapter new textboxes
Viruses that infect plants are responsible for reduction in both yield and quality of crops around the world, and thus are of great economic importance. This has provided the impetus for the extensive research into the molecular and cellular biology of these pathogens and into their interaction with their plant hosts and their vectors. However, interest in plant viruses extends beyond their ability to damage crops. Many plant viruses - for example, tobacco mosaic virus - have been used as model systems to provide basic understanding of how viruses express genes and replicate. Others permitted the elucidation of the processes underlying RNA silencing, now recognized as a core epigenetic mechanism underpinning numerous areas of biology. This book attests to the huge diversity of research in plant molecular virology. Written by world authorities in the field, the book opens with two chapters on the translation and replication of viral RNA. Following chapters cover topics such as viral movement within and between plants, plant responses to viral infection, antiviral control measures, virus evolution, and newly emerging plant viruses. The book concludes with two chapters on biotechnological applications of plant viruses. Throughout, the focus is on the most recent, cutting-edge research, making this book essential reading for everyone working with plant viruses.
Virology is a clear and accessible introduction to this fast moving field, providing a comprehensive resource enabling students to understand the key concepts surrounding this exciting subject. The authors have produced a text that stimulates and encourages the student through the extensive use of clear, colour-coded diagrams. Taking a modern approach to the subject, the relevance of virology to everyday life is clearly emphasised and discussion on emerging viruses, cancer, vaccines, anti-viral drugs gene vectors and pesticides is included. This title: Provides an introduction to the theories behind the origins of viruses and how they are evolving with discussion on emerging viruses Includes numerous diagrams with standard colour coding for different types of molecule such as DNA, messenger RNA, other virus RNA’s proteins – all diagrams are carefully developed and clearly labelled to enhance student understanding Features self-contained descriptions of the complete replication cycles of a selection of viruses Introduces the relevance of virology to the modern world including the latest developments in the field - HIV, Foot and Mouth disease, Ebola, SARS and MMR Presents summary boxes, further reading and an associated website to include the latest developments Virology is an essential textbook for all undergraduate students of biology, microbiology and biomedical sciences taking courses in virology. It is also an invaluable resource for MSc level students who have previously done little or no virology and are looking for an accessible introduction to the subject.

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