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Viruses: Biology, Application, and Control is a concise textbook for advanced undergraduate and graduate students covering the essential aspects of virology included in biomedical science courses. It is an updated and expanded version of David HarperĀs Molecular Virology, Second Edition. Focusing on key mechanisms and developments, Viruses presents many new sections that cover recent advances including virus evolution, emerging infections, virus extinction, control of infections, antiviral drugs, gene therapy, bacteriophage therapy, and diagnostics. The first chapters introduce the reader to the structure and nature of viruses, including their classification and evolution. As viruses cause widespread and serious disease, the ensuing chapters explain how they interact with the immune system and the different ways we try to defeat them: vaccines, antiviral drugs, and immunotherapy. There is also coverage of laboratory methods for viral detection and laboratory diagnosis. While viruses do cause disease, many do not, and their special biology means they can have beneficial uses. This aspect of viruses is not neglected. Finally, one of the most interesting areas in virology, and one given extensive coverage here, is how new viruses emerge and establish themselves. Viruses: Biology, Application, and Control is a rigorous treatment of the molecular side of virology and its conceptual approach makes it an essential text for students and non-specialists.
Expanded version of Molecular virology / David Harper. 2nd ed. 1998.
Mass Production of Beneficial Organisms: Invertebrates and Entomopathogens is an essential reference and teaching tool for researchers in developed and developing countries working to produce "natural enemies" in biological control and integrated pest management programs. As we become aware of the negative impact of pesticides in human health and on the environment, interest is rapidly increasing in developing biological pest control alternatives. Tremendous advances have been made in beneficial organism technology, such as insect predators and parasitoids, mite predators, entomopathogenic nematodes, fungi, bacteria, and viruses. However, developing techniques to mass produce these biological control agents is not enough if the cost of commercialization is prohibitive. Advancing mass production to the level of economic feasibility is critical, so these new technologies can compete in the open market. This book educates academic and industry researchers, and enables further development of mass production so new technologies can compete in the open market. It is also an excellent resource for those researching beneficial arthropod mass production and technologies for other uses, including for study and application in biotechnology and biomedical research. Focuses on techniques for mass production of beneficial organisms and methods of evaluation and quality assessment Organizes and presents the most advanced and current knowledge on methods to mass produce beneficial organisms in response to the increased global demand for alternatives to chemical pesticides for biological control producers Includes a team of highly respected editors and authors with broad expertise in these areas
For many years the use of chemical agents such as pesticides and herbicides has been effective in controlling the many varieties of pests that infest both agricultural crops and backyard gardens. However, these pests are gradually becoming resistant to these agents, because the agents themselves are acting as selective factors making the pests better and better able to resist and persist. As a result, the use of biological controlling agents is increasing. This book is a comprehensive and authoritative handbook of biological control. Key Features * Introduction (preface plus 2 chapters) * Principles and processes (12 chapters) * Agents, biology, and methods (6 chapters) * Applications (10 chapters) * Research (2 chapters)
Best-selling textbook fills the gap between introductory texts and advanced reviews of major virus families. Focuses on concepts and principles to present a comprehensive treatment from molecular biology to pathogenesis and control of viral infections. Illustrates why and how animal viruses are studied and demonstrates how the knowledge gained from such model viruses can be used to study viral systems that are still relatively unknown. Provides a thorough introduction to principles of viral pathogenesis, a broad view of viral evolution, a discussion of how viruses were discovered, and an explanation of the history of the discipline of virology.
Viruses that infect plants are responsible for reduction in both yield and quality of crops around the world, and thus are of great economic importance. This has provided the impetus for the extensive research into the molecular and cellular biology of these pathogens and into their interaction with their plant hosts and their vectors. However, interest in plant viruses extends beyond their ability to damage crops. Many plant viruses - for example, tobacco mosaic virus - have been used as model systems to provide basic understanding of how viruses express genes and replicate. Others permitted the elucidation of the processes underlying RNA silencing, now recognized as a core epigenetic mechanism underpinning numerous areas of biology. This book attests to the huge diversity of research in plant molecular virology. Written by world authorities in the field, the book opens with two chapters on the translation and replication of viral RNA. Following chapters cover topics such as viral movement within and between plants, plant responses to viral infection, antiviral control measures, virus evolution, and newly emerging plant viruses. The book concludes with two chapters on biotechnological applications of plant viruses. Throughout, the focus is on the most recent, cutting-edge research, making this book essential reading for everyone working with plant viruses.
Interferons (IFNs) play pivotal roles in shaping the immune responses in mammals and are particularly important for the control of viral infections, cell growth, and immune regulation. These proteins rapidly induce an "anti-viral state" in cells that surround infected cells. In order to survive, viruses have evolved with multiple strategies to evade the anti-viral effects of IFNs. Elucidating the molecular and cellular biology of the virus-interferon interaction is key to understanding issues, such as viral pathogenesis, latency, and the development of novel antivirals. In this book, international experts review current research topics, producing a timely overview of this exciting field. The book opens with a chapter that comprehensively reviews the antiviral effects of extracellular double-stranded RNA - the "viral toxin." This is followed by chapters that review the properties of type I and type III interferons, and the role of interferon-stimulated genes. Additional chapters are devoted to understanding the diverse strategies used by clinically-relevant human viruses to subvert host interferon responses. The book closes with an interesting overview of the clinical application of interferons as antiviral and anticancer agents. It will be essential reading for every scientist involved in interferon or antiviral research and will be a recommended text for all virology laboratories.