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In this thesis, I will argue that the Darwinian paradigm is no longer the best explanation for biological observations. When compared with a post-Darwinism paradigm, one that includes Darwinian explanations where appropriate, non-Darwinian unintelligent explanations where appropriate, and intelligent explanations where appropriate, I argue that the Darwinian paradigm has less explanatory power. Consequently, Darwinism should be rejected by science as the dominant paradigm and a new paradigm, a post-Darwinism paradigm, is the best explanation for observations in biology. By revealing where Darwinism has shortcomings, and demonstrating how a competing theory, namely, intelligent design, can provide a better explanation, I argue that something more than Darwinian mechanisms are required to explain all observations in biology. I argue that a new paradigm that permits postulating non-Darwinian mechanisms ought not to be considered wrong due to prior commitments to philosophical naturalism, and that such a paradigm is reasonable to embrace.