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Make the leap from introductory to organic chemistry The transition from first-year chemistry to an organic chemistry course can be a challenge for many students. Not only must they recall their first-year studies of bonding, structure, and reactivity, but they must also master a whole new set of nomenclature, along with the critical skill of "electron-pushing." Reviewing the fundamentals and carefully introducing the important new concepts, The Bridge to Organic Chemistry: Concepts and Nomenclature helps students smoothly bridge the gap to organic chemistry. Concise and carefully structured, The Bridge to Organic Chemistry helps students strengthen their mastery of fundamental concepts from an introductory chemistry course and then introduces them to the new concepts of organic chemistry. Step by step, the reader will: Review important concepts such as structural isomerism, Lewis formulas, hybridization, and resonance and understand their roles in modern organic chemistry Learn organic nomenclature along with the critical skill of "electron-pushing" Explore mechanisms that utilize many of the concepts: Lewis acid-base chemistry, rate laws, enthalpy changes, bond energies and electronegativities, substituent effects, structure, stereochemistry, and the visualization of electron flow through the electron-pushing model With a clear progressive style and substantial review at each step, The Bridge to Organic Chemistry puts organic chemistry and its nomenclature within the grasp of every student.
Organic Chemistry Concepts and Applications for Medicinal Chemistry provides a valuable refresher for understanding the relationship between chemical bonding and those molecular properties that help to determine medicinal activity. This book explores the basic aspects of structural organic chemistry without going into the various classes of reactions. Two medicinal chemistry concepts are also introduced: partition coefficients and the nomenclature of cyclic and polycyclic ring systems that comprise a large number of drug molecules. Given the systematic name of a drug, the reader is guided through the process of drawing an accurate chemical structure. By emphasizing the relationship between structure and properties, this book gives readers the connections to more fully comprehend, retain, apply, and build upon their organic chemistry background in further chemistry study, practice, and exams. Focused approach to review those organic chemistry concepts that are most important for medicinal chemistry practice and understanding Accessible content to refresh the reader's knowledge of bonding, structure, functional groups, stereochemistry, and more Appropriate level of coverage for students in organic chemistry, medicinal chemistry, and related areas; individuals seeking content review for graduate and medical courses and exams; pharmaceutical patent attorneys; and chemists and scientists requiring a review of pertinent material
Based on the premise that many, if not most, reactions in organic chemistry can be explained by variations of fundamental acid–base concepts, Organic Chemistry: An Acid–Base Approach provides a framework for understanding the subject that goes beyond mere memorization. Using several techniques to develop a relational understanding, it helps students fully grasp the essential concepts at the root of organic chemistry. This new edition was rewritten largely with the feedback of students in mind and is also based on the author’s classroom experiences using the first edition. Highlights of the Second Edition Include: Reorganized chapters that improve the presentation of material Coverage of new topics, such as green chemistry Adding photographs to the lectures to illustrate and emphasize important concepts A downloadable solutions manual The second edition of Organic Chemistry: An Acid–Base Approach constitutes a significant improvement upon a unique introductory technique to organic chemistry. The reactions and mechanisms it covers are the most fundamental concepts in organic chemistry that are applied to industry, biological chemistry, biochemistry, molecular biology, and pharmacy. Using an illustrated conceptual approach rather than presenting sets of principles and theories to memorize, it gives students a more concrete understanding of the material.
Hellwinkel gives a short and general introduction to the systematic nomenclature of organic compounds. On the basis of carefully selected examples it offers simple and concise guidelines for the generation of systematic compound names as codified by the IUPAC rules. Besides the most common compound classes important special areas such as cyclophanes, carbohydrates, organometallic and isotopically modified compounds and stereochemical specifications are dealt with. In cases where there is not yet a finalised set of IUPAC rules, possibilities for logical and desirable extensions of existing rules are outlined. Likewise, deviations from Chemical Abstracts and Beilstein index names are noted, if significant. The German version (4th edition) is meanwhile a longseller.
Aimed at pre-university and undergraduate students, this volume surveys the current IUPAC nomenclature recommendations in organic, inorganic and macromolecular chemistry.
Diazo compounds play an important role as reaction intermediates and reagents in organic synthesis. This book is a critical, well- referenced and eminently readable introduction to the chemistry of aliphatic, inorganic and organometallic diazo compounds. It provides well-researched information that could otherwise be obtained only by costly and time-consuming searches of multi-volume treatises and the original literature. Topics covered in depth include: - preparation and structure of diazo compounds - kinetics and mechanism of diazotizations - reactions of diazo compounds - applications in organic synthesis - metal complexes with diazonium and diazo compounds Many tables and reaction schemes as well as copious literature citations make this book a highly valuable reference work for synthetic organic chemists, inorganic chemists, organometallic chemists and industrial chemists. Already available: Volume 1 of Diazo Chemistry covering aromatic and heteroaromatic compounds.
Chemistry was at one time completely described in terms of collision theo ry, in which one molecule collided with another, sometimes producing reac tion. Then came the realization that enzymes which are highly efficient ca talysts, work by way of prior complexation, often stereospecific, which is then followed by chemical reaction. Thus, systems that exhibit "host-guest" relationships, i.e., that show complexing are being looked at an ever in creasing frequency. The cyclodextrins are the first and probably the most important example of compounds that exhibits complex formation. This is a book about the cyclodextrins. There are of course other compounds that exhibit "host-guest" relationships and thus bind other organic molecules, but so far they have not achieved the importance of the cyclodextrins. By their name it is obvious that cyclodextrins are cyclic compounds. The complexes that they form are therefore cyclic inclusion complexes. Because the complexes are cyclic in nature, complexation can be very strong, as op posed to 1t-complex, electrostatic, or apolar complexes in which complex formation is two-dimensional rather than three-dimensional. Cyclodextrins turn out to be excellent models of enzymes. This is proba bly not fortuitous because they were first sought since it was discovered that the principal binding in the enzyme chymotrypsin was a cyclic inclusion complex. Cyclodextrins can do more than form cyclic inclusion complexes, they can catalyze as well. But catalysis always occurs after complex formation.

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