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An important translational book bridging the gap between science and clinical medicine, Prostate Cancer reviews the biological processes that can be implicated in the disease, reviews current treatments, highlighting the pitfalls where relevant and examines the scientific developments that might result in novel treatments in the future. Key Features * Provides a translational resource for scientists and clinicians working on prostate cancer * Reviews current surgical interventions and highlights their related pitfalls * Presents the latest laparoscopic techniques with figures and illustrations of step-by-step procedures * Offers insight into the potential for novel approaches to treatment in the future * Includes personal perspectives from patients
This book effectively summarizes our knowledge of recent advances in prostate cancer. It focuses on our state-of-the-art understanding of risk factors, prevention, detection, prognosis and treatment of prostate cancer and identifies basic science findings that are being translated into clinical practice. In addition, the book singles out key areas of research that have potential for clinical translation. Both basic scientists and clinicians will be invited to provide up-to-date reviews in each area of prostate cancer. During the last decade the pace of clinical discovery and the scientific advances in prostate cancer have been very rapid. For instance, currently there are more than 100 drugs in the pharmaceutical pipeline that have the potential for clinical management of prostate cancer. Therefore, it has been very difficult for clinicians and basic scientists to keep pace with the field as a whole. Recently, some of these discoveries are already having an impact on clinical practice. For example, the discovery of the androgen receptor gene amplification in prostate cancer has led to the development of a OC super-antiandrogenOCO, which is being tested in clinical trials. Also, recent knowledge of androgen synthesis in prostate cancer cells has led to clinical trials with steroid-metabolism inhibitors. Finally, robotic surgery has also dramatically changed clinical practice. Thus, this important book serves to provide readers with a one-stop overview of the field of prostate cancer research and its translation into the clinical arena."
The book summarizes developments in all areas of urological cancer including clinical and molecular advances. The aim of the book is to educate urologists and oncologists so that they are able to understand scientific developments within urological oncology and be up-to-date with clinical practice in this area. The book includes both guidelines for clinical practice and synopses of advances in science research. This practical handbook provides a distillation of current practice and research for oncologists and urologists in clinical practice. Its author has published eleven books on cancer and is the founder of the "Prostate Cancer Charity".
Biotargets of Cancer in Current Clinical Practice presents an updated and reasoned review of the current status of knowledge concerning the major cancer types with a special focus on the current biomarkers, genes involved and the potential future targets of innovative therapies. The volume includes for each major cancer type, a comprehensive although concise discussion of epidemiology, affirmed and innovative biomarkers for diagnosis, and descriptions of the relevant genes for prognosis and (individualized) therapy through biotarget-specific new molecular treatments, with the latest information on the validation status of each novel biomarker. Individual chapters are dedicated to the major cancer types, plus a special chapter on metastasis. The present debate on patentability of genetic information applied to diagnostics and therapeutics of cancer is also discussed.
A simple introduction explaining the broad principles underlying chemotherapy, this book gives trainees a framework within which they can place the specific aspects of cancer chemotherapy they encounter in their everyday experience. The first part of this book is unique in explaining the recent developments in the field in terms of their point of action in the natural history of cancer. The second and third sections contain a more straightforward description of practical aspects of chemotherapy, and the current place of drug treatment in everyday cancer management, including the outcomes of that treatment.
Neuro-oncology has evolved substantially as a clinical and research discipline over the past few decades. Cancer Neurology in Clinical Practice: Neurologic Complications of Cancer and its Treatment, Second Edition provides clinicians from various backgrounds and levels of training with a reference to help focus the differential diagnosis, treatment strategy, and management plan for the cancer patient with neurologic symptoms and findings. The volume begins with an overview of the field of neuro-oncology and a review of the role of neuroimaging in the diagnosis of neuro-oncologic disease. Several chapters on interpretation and management of common neuro-oncologic symptoms follow. Subsequent sections contain chapters on the direct and indirect neurologic complications of cancer as well as complications of therapy. The final section focuses on the spectrum and management of neurologic disease in patients with cancer of specific organs. Cancer Neurology in Clinical Practice: Neurologic Complications of Cancer and its Treatment, Second Edition is an important new work that aims to broaden and deepen the familiarity of clinicians with the range and management of neuro-oncologic diseases in order to improve the quality of care for cancer patients.
“... Useful background information is displayed in blue boxes, and good use is made of numerous tables and diagrams... a useful book for the undergraduate medical or allied health professional...” –Oncology News, May/June 2010 This forward looking cancer biology book appeals to a wide ranging audience. Introductory chapters that provide the molecular, cellular, and genetic information needed to comprehend the material of the subsequent chapters bring unprepared students up to speed for the rest of the book and serve as a useful refresher for those with previous biology background. The second set of chapters focuses on the main cancers in terms of risk factors, diagnostic and treatment methods and relevant current research. The final section encompasses the immune system’s role in the prevention and development of cancer and the impact that the Human Genome Project will have on future approaches to cancer care. While best suited to non-majors cancer biology courses, the depth provided satisfies courses that combine both majors and non-majors. Also, and deliberately, the authors have incorporated relevant information on diagnosis and treatment options that lend appeal to the lay reader.

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