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Examines the relationship among cells, genes, and the environment and of the obstacles and achievements of molecular biologists attempting to understand how to "build" a human body.
This book addresses possible analogies between cancer and developmental biology. An international group of experts provides a multidisciplinary approach, allowing biological or clinical scientists involved with cancer research to integrate specific information from diverse areas. Five concepts of cancer are presented, and developmental biology is reviewed at five levels. These are integrated in discussions of failure in organisation as a basis of cancer and its control. The book will be a valuable reference for both newcomers as well as experienced biological and clinical scientists. Features
This book captivates student interest, opening minds to the wonder of developmental biology, whilst covering required material with scientific rigour. The tenth edition reflects the exciting new age of genomics, genetic regulatory networks and digital visualization techniques while keeping focus on the major questions of animal development.
A much awaited textbook, Developmental Biology covers the entire gamut of animal development, from gametogenesis to senescence and cell death. Fertilization, cleavage, gastrulation, organ formation and fetal membranes, experimental embryology, developmental processes after embryogenesis, and environmental regulation of animal development are discussed in different chapters. Many chapters integrate descriptive embryology with modern concepts in developmental biology. Developmental genetics of Drosophila also finds a spot in the book.
"A concise account of what we know about development discusses the first vital steps of growth and explores one of the liveliest areas of scientific research."--P. [2] of cover.
In this book, tumour growth is perceived as a deviation from the normal development of the human organism. The molecular, cellular, and tissue determinants of different tumours are discussed showing that each is a different disease, often corresponding to a particular developmental stage. The natural history of several cancers illustrates how clinical incidence can be just the visible part of the iceberg, while the first changes at the tissue level sometimes occur several years before tumour growth becomes manifest. Several mechanisms are proposed to explain the distribution of cancers during the human life span and the decline of the incidence of cancers during human senescence.
No field of contemporary biomedical science has been more revolutionized by the techniques of molecular biology than developmental biology. This is an outstanding concise introduction to developmental biology that takes a contemporary approach to describing the complex process that transforms an egg into an adult organism. The book features exceptionally clear two-color illustrations, and is designed for use in both undergraduate and graduate level courses. The book is especially noteworthy for its treatment of development in model organisms, whose contributions to developmental biology were recognized in the 1995 Nobel Prize for physiology and medicine.

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