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The book, now in its Third Edition, continues to offer the basic concepts and principles of biochemical engineering. It covers the curriculum for a first-course in Biochemical Engineering at the undergraduate level of Chemical Engineering discipline and also caters to the requirements of BTech Biotechnology and BSc Biotechnology offered by various universities. The text first explains the basics of microbiology and biochemistry before moving on to explore the significance of enzymes, their properties, types, kinetics, industrial applications, production and formulation and the methods of their immobilization. It also deals with cell growth and its kinetic aspects and discusses various types of biological reactors with an emphasis on key engineering practices related to fermentation processes and products, bioreactor design and operation. It offers a complete description on downstream processing and control of microorganisms. Besides, it also covers in the appendices some important topics such as process kinetics and reactor analysis, bioenergetics, and environmental microbiology to justify their relevance in biochemical engineering. NEW TO THIS EDITION : Offers a complete description with applications and configurations of membrane bioreactors (Chapter 7). Presents a facelift of downstream processes in the topics, viz. disruption of cells supported with flow sheet, freeze drying, formulation, etc. along with a total revamping of the discussion on supercritical fluid extraction and induction of biofouling (Chapter 9). Provides a new appendix—Appendix D—on Self-Assessment Exercises, which incorporates questions in the form of multiple choice, true/false and fill in the blanks in order to assess the level of understanding.
This work provides comprehensive coverage of modern biochemical engineering, detailing the basic concepts underlying the behaviour of bioprocesses as well as advances in bioprocess and biochemical engineering science. It includes discussions of topics such as enzyme kinetics and biocatalysis, microbial growth and product formation, bioreactor design, transport in bioreactors, bioproduct recovery and bioprocess economics and design. A solutions manual is available to instructors only.
Current demand in biomedical sciences emphasizes the understanding of basic mechanisms and problem solving rather than rigid empiricism and factual recall. Knowledge of the basic laws of mass and momentum transport as well as model development and validation, biomedical signal processing, biomechanics, and capstone design have indispensable roles in the engineering analysis of physiological processes. To this end, an introductory, multidisciplinary text is a must to provide the necessary foundation for beginning biomedical students. Assuming no more than a passing acquaintance with molecular biology, physiology, biochemistry, and signal processing, Biomedical Engineering Principles, Second Edition provides just such a solid, accessible grounding to this rapidly advancing field. Acknowledging the vast range of backgrounds and prior education from which the biomedical field draws, the organization of this book lends itself to a tailored course specific to the experience and interests of the student. Divided into four sections, the book begins with systems physiology, transport processes, cell physiology, and the cardiovascular system. Part I covers systems analysis, biological data, and modeling and simulation in experimental design, applying concepts of diffusion, and facilitated and active transport. Part II presents biomedical signal processing, reviewing frequency, periodic functions, and Fourier series as well as signal acquisition and processing techniques. Part III presents the practical applications of biomechanics, focusing on the mechanical and structural properties of bone, musculoskeletal, and connective tissue with respect to joint range, load bearing capacity, and electrical stimulation. The final part highlights capstone design, discussing design perspectives for living and nonliving systems, the role of the FDA, and the project timeline from inception to proof of concept. Cutting across many disciplines, Biomedical Engineering Principles, Second Edition offers illustrative examples as well as problems and discussion questions designed specifically for this book to provide a readily accessible, widely applicable introductory text.
Written by renowned professors drawing on their experience gained in the world's most innovative biotechnology market, Japan, this advanced textbook provides an excellent and comprehensive introduction to the latest developments in the field. It provides an array of questions & answers and features numerous applied examples, extending to industrial applications with chapters on medical devices and downstream operations in bioprocesses. Useful for students studying the fundamentals of biochemical engineering, as well as for chemical engineers already working in this vital and expanding field.
This welcome new edition covers bioprocess engineering principles for the reader with a limited engineering background. It explains process analysis from an engineering point of view, using worked examples and problems that relate to biological systems. Application of engineering concepts is illustrated in areas of modern biotechnology such as recombinant protein production, bioremediation, biofuels, drug development, and tissue engineering, as well as microbial fermentation. The main sub-disciplines within the engineering curriculum are all covered; Material and Energy Balances, Transport Processes, Reactions and Reactor Engineering. With new and expanded material, Doran's textbook remains the book of choice for students seeking to move into bioprocess engineering. NEW TO THIS EDITION: All chapters thoroughly revised for current developments, with over 200 pgs of new material, including significant new content in: Metabolic Engineering Sustainable Bioprocessing Membrane Filtration Turbulence and Impeller Design Downstream Processing Oxygen Transfer Systems Over 150 new problems and worked examples More than 100 new illustrations New to this edition: All chapters thoroughly revised for current developments, with over 200 pgs of new material, including significant new content in: Metabolic Engineering Sustainable Bioprocessing Membrane Filtration Turbulence and Impeller Design Downstream Processing Oxygen Transfer Systems Over 150 new problems and worked examples More than 100 new illustrations
This text is intended to provide students with a solid grounding in basic principles of biochemical engineering. Beginning with a historical review and essential concepts of biochemical engineering in part I, the next three parts are devoted to a comprehensive discussion of various topics in the areas of life sciences, kinetics of biological reactions and engineering principles. Having described the different building blocks of life, microbes, metabolism and bioenergetics, the book proceeds to explain enzymatic kinetics and kinetics of cell growth and product formation. The engineering principles cover transport phenomena in bioprocess systems and various bioreactors, downstream processing and environmental technology. Finally, the book concludes with an introduction to recombinant DNA technology. This textbook is designed for B.Tech. courses in biotechnology, B.Tech. courses in chemical engineering and other allied disciplines, and M.Sc. courses in biotechnology.

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