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Discover how analytical chemistry supports the latest clinical research This book details the role played by analytical chemistry in fostering clinical research. Readers will discover how a broad range of analytical techniques support all phases of clinical research, from early stages to the implementation of practical applications. Moreover, the contributing authors' careful step-by-step guidance enables readers to better understand standardized techniques and steer clear of everyday problems that can arise in the lab. Analytical Techniques for Clinical Chemistry opens with an overview of the legal and regulatory framework governing clinical lab analysis. Next, it details the latest progress in instrumentation and applications in such fields as biomonitoring, diagnostics, food quality, biomarkers, pharmaceuticals, and forensics. Comprised of twenty-five chapters divided into three sections exploring Fundamentals, Selected Applications, and Future Trends, the book covers such critical topics as: Uncertainty in clinical chemistry measurements Metal toxicology in clinical, forensic, and chemical pathology Role of analytical chemistry in the safety of drug therapy Atomic spectrometric techniques for the analysis of clinical samples Biosensors for drug analysis Use of X-ray techniques in medical research Each chapter is written by one or more leading pioneers and experts in analytical chemistry. Contributions are based on a thorough review and analysis of the current literature as well as the authors' own firsthand experiences in the lab. References at the end of each chapter serve as a gateway to the literature, enabling readers to explore individual topics in greater depth. Presenting the latest achievements and challenges in the field, Analytical Techniques for Clinical Chemistry sets the foundation for future advances in laboratory research techniques.
This practical introduction to all the elextroanalytical techniques that are used in clinical chemistry and laboratory medicine is the only in-depth treatment of the subject available. The author presents the relevant theory and uses numerous examples to illustrate the scope and possibilities of electroanalysis in the clinical laboratory. The material covered includes the principles and bioanalytical applications of voltammetry and potentiometry, electrochemical biosensors, detectors to flowing steams, and in vivo electrochemistry. The book should be useful to those considering the use of electroanalysis in their laboratories and to clinical chemists experienced in electroanalysis
In its Seventh Edition, this acclaimed Clinical Chemistry continues to be the most student-friendly clinical chemistry text available. This edition not only covers the how of clinical testing but also places greater emphasis on the what, why, and when in order to help today's students fully understand the implications of the information covered, as well as the applicability of this crucial topic in practice. With clear explanations that strike just the right balance of analytic principles, techniques, and correlation of results with disease states, this edition has been fully updated with the latest information to help keep today's students at the forefront of today's science. New case studies, practice questions, and exercises provide ample opportunities to review and apply the topics covered through the text.
A condensed, easier-to-understand student version of the acclaimed Tietz Textbook of Clinical Chemistry and Molecular Diagnostics, Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics, 7th Edition uses a laboratory perspective in providing the clinical chemistry fundamentals you need to work in a real-world, clinical lab. Coverage ranges from laboratory principles to analytical techniques and instrumentation, analytes, pathophysiology, and more. New content keeps you current with the latest developments in molecular diagnostics. From highly respected clinical chemistry experts Carl Burtis and David Bruns, this textbook shows how to select and perform diagnostic lab tests, and accurately evaluate results. Authoritative, respected author team consists of two well-known experts in the clinical chemistry world. Coverage of analytical techniques and instrumentation includes optical techniques, electrochemistry, electrophoresis, chromatography, mass spectrometry, enzymology, immunochemical techniques, microchips, automation, and point of care testing. Learning objectives begin each chapter, providing measurable outcomes to achieve after completing the material. Key words are listed and defined at the beginning of each chapter, and bolded in the text. A glossary at the end of the book makes it quick and easy to look up definitions of key terms. More than 500 illustrations plus easy-to-read tables help you understand and remember key concepts. New chapters on molecular diagnostics include the principles of molecular biology, nucleic acid techniques and applications, and genomes and nucleic acid alterations, reflecting the changes in this rapidly evolving field. New content on clinical evaluation of methods, kidney function tests, and diabetes is added to this edition. NEW multiple-choice review questions at the end of each chapter allow you to measure your comprehension of the material. NEW case studies on the Evolve companion website use real-life scenarios to reinforce concepts.
Designed to serve as a student textbook, it is also valuable as a reference book for practicing professionals. This book will emphasize theory, concepts, correlations, and applications; it will also include principles of analytical techniques, though it is not designed to be a technical manual. This excellent text and reference provides detailed discussions on the basic principles of clinical chemistry, including carbohydrates, lipids, proteins and enzymes, renal function, and liver function. Coverage also includes electrolytes and acid base balance, endocrine function and related disorders, G.I. and pancreatic function, nutrition, special testing, and more.
Quantitative calculations are common everyday practice for the analytical chemist in his laboratory work. This book aims at familiarizing students and technicians with such calculations done in pharmaceutical analysis, biopharmaceutics, pharmacokinetics, pharmacy practice, pharmaceutical chemistry, physical pharmacy and radiopharmacy. It exposes the reader to various approaches for problem solving and aids in consolidating theoretical knowledge by applying it to the solution of real problems. Structured in 15 chapters, each one containing a short introduction of the relevant theory and equations to facilitate the comprehension of theoretical principles and the solution of the relevant problems.

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