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This book contains the most comprehensive coverage available anywhere for two-level factorial designs. The re-analysis of 50 published examples serves as a how-to guide for analysis of the many types of full factorial and fractional factorial designs. By focusing on two-level designs, this book is accessible to a wide audience of practitioners who use planned experiments.
Heterocyclic amines (HCAs) are a class of toxicological compounds that can be formed during heating of precursors, amino acids, creatinine, creatine, and sugars at high temperature cooking of muscle products. These potent mutagens are suspected to play a role in human cancers. The objective of this study was to investigate a practical method to reduce the amount of HCAs through marinating of beef steaks. We were interested in the potential health benefits of natural extracts containing polyphenols present in commercial marinades. HCAs were compared in marinated and unmarinated steaks. Four common HCAs were investigated: 2-amino-3,8- dimethyl-imidazo[4,5-f]quinoxaline (MeIQx), 2-amino-1-methyl-6-phenyl-imidazo[4,5- b]pyridine (PhIP), 1-methyl-9H-pyrido[4,3-b]-indol (harman), and 9H-pyrido[4,3-b]-indol (norharman). Steaks were marinated for one hour and grilled at 400 °F for 5 minutes at each side. Meat samples were extracted by solid phase extraction (SPE) and analysis with HPLC showed the significant decrease (p
The last twenty years have witnessed a significant growth of interest in optimal factorial designs, under possible model uncertainty, via the minimum aberration and related criteria. This book gives, for the first time in book form, a comprehensive and up-to-date account of this modern theory. Many major classes of designs are covered in the book. While maintaining a high level of mathematical rigor, it also provides extensive design tables for research and practical purposes. Apart from being useful to researchers and practitioners, the book can form the core of a graduate level course in experimental design.
Multivariate normal and t probabilities are needed for statistical inference in many applications. Modern statistical computation packages provide functions for the computation of these probabilities for problems with one or two variables. This book describes recently developed methods for accurate and efficient computation of the required probability values for problems with two or more variables. The book discusses methods for specialized problems as well as methods for general problems. The book includes examples that illustrate the probability computations for a variety of applications.
Statistical Analysis of Management Data provides a comprehensive approach to multivariate statistical analyses that are important for researchers in all fields of management, including finance, production, accounting, marketing, strategy, technology, and human resources. This book is especially designed to provide doctoral students with a theoretical knowledge of the concepts underlying the most important multivariate techniques and an overview of actual applications. It offers a clear, succinct exposition of each technique with emphasis on when each technique is appropriate and how to use it. This third edition, fully revised, updated, and expanded, reflects the most current evolution in the methods for data analysis in management and the social sciences. In particular, this edition includes: · A new chapter on the analysis of mediation and moderation effects · Examples using STATA for most of the statistical methods · Example of XLSTAT applications Featuring numerous examples, the book may serve as an advanced text or as a resource for applied researchers in industry who want to understand the foundations of the methods particularly relevant and typically used in management research, and to learn how they can be applied using widely available statistical software.
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A culmination of the author’s many years of consulting and teaching, Design and Analysis of Experiments with SAS provides practical guidance on the computer analysis of experimental data. It connects the objectives of research to the type of experimental design required, describes the actual process of creating the design and collecting the data, shows how to perform the proper analysis of the data, and illustrates the interpretation of results. Drawing on a variety of application areas, from pharmaceuticals to machinery, the book presents numerous examples of experiments and exercises that enable students to perform their own experiments. Harnessing the capabilities of SAS 9.2, it includes examples of SAS data step programming and IML, along with procedures from SAS Stat, SAS QC, and SAS OR. The text also shows how to display experimental results graphically using SAS ODS graphics. The author emphasizes how the sample size, the assignment of experimental units to combinations of treatment factor levels (error control), and the selection of treatment factor combinations (treatment design) affect the resulting variance and bias of estimates as well as the validity of conclusions. This textbook covers both classical ideas in experimental design and the latest research topics. It clearly discusses the objectives of a research project that lead to an appropriate design choice, the practical aspects of creating a design and performing experiments, and the interpretation of the results of computer data analysis. SAS code and ancillaries are available at http://lawson.mooo.com

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